Medical & Clinical Research

Here are our publications in these therapeutic areas

Immunology and Inflammation Oncology Cardiovascular Metabolic Theoretical Principles sidekick doctor

Immunology and Inflammation

Digital health programme improves quality of life in rheumatoid arthritis: a retrospective analysis of real-world data

Clinical and Experimental Rheumatology

Dobies, B., White, A. J., Isberg, A., Gudmundsson, S. F., & Oddsson, S.

Peer-reviewed paper

Engagement, Retention, and Acceptability in a Digital Health Program for Atopic Dermatitis: Prospective Interventional Study

JMIR Formative Research (2023), 7(1), e41227

Gudmundsdóttir SL, Ballarini T, Ámundadóttir ML, Mészáros J, Eysteinsdottir JH, Thorleifsdottir RH, Hrafnkelsdóttir SK, Helgadottir H, Oddsson S, & Silverberg JI.

Peer-reviewed paper

Feasibility of a Digital Therapeutic Program for Patients with Atopic Dermatitis: Analysis of Engagement, Retention and Acceptability

ActaDV Vol. 102 (2022): Supplement 223.

Gudmundsdóttir SL, Ballarini T, Ámundadóttir ML, Mészáros J, Hrafnkelsdóttir SK., Oddsson S.

conference abstract

Clinical Efficacy of a Digital Intervention for Patients with Atopic Dermatitis: a Prospective Single Center Study

Dermatology and Therapy. 2022;12:2601–11.

Gudmundsdóttir SL, Ballarini T, Ámundadóttir ML, Mészáros J, Eysteinsdóttir JH, Thorleifsdóttir RH, Hrafnkelsdóttir SK, Bragadóttir HB, Oddsson S, Silverberg JI

peer reviewed paper

High engagement and improved energy levels among RA and PsA patients in a tailored digital support program in a real-world setting.

Poster presented at: 3rd Digital Rheumatology Day, Lausanne, Switzerland. May 6 2021

Oddsson S, Helgadottir H, Amundadottir M, Ylanne K, Loftsson K, Thorgeirsson T.

conference abstract

A21 A digital treatment support program for RA and PsA patients in a real-world setting. High patient engagement and improved energy levels.

Reuma Bulletin, 2021;147(4):29. Abstracts of eReumadagarna, Stockholm, Sweden. September 16-17, 2021.

Oddsson S, Loftsson K, Ámundadóttir ML, Ylänne K, Helgadóttir H, Thorgeirsson T.

conference abstract

P376 Improving Stress and Fatigue in a real-world setting among patients with Inflammatory Bowel Disease through a digital platform.

Journal of Crohn's and Colitis, 2021; 15(Suppl1): S391–S392. Abstracts of the 16th Congress of ECCO Virtual, July 2-3 & 8-10, 2021.

Oddsson S, Gunnarsdottir T, Johannsdottir L, Amundadottir ML, Frimannsdottir A, Ylanne K, Molander P, Islind A, Oskarsdottir M, Thorgeirsson T.

conference abstract

P487 The Feasibility of a Digital Platform for Improving Disease Management Among Patients With Ulcerative Colitis.

Journal of Crohn's and Colitis, 2021; 15(Suppl1): S474. Abstracts of the 16th Congress of ECCO Virtual, July 2-3 & 8-10, 2021

Oddsson S., Gunnarsdottir T, Ylanne, K, Molander P, Thorgeirsson T.

conference abstract

A Digital Therapeutic Solution for Atopic Dermatitis; Protocol for a Nonrandomized, Single-Arm, Interventional Trial.

Br J Dermatol, 2022;186: e135-e173. Revolutionizing Atopic Dermatitis, 11–13 December 2021.

Gudmundsdottir SL, Eysteinsdottir J, Þorleifsdottir RH, Ulfsdottir H, Reykdal E, Hrafnkelsdottir SK, Bragadottir HB, Oddsson S, Silverberg J.

conference abstract

A Novel Digital Therapeutic Intervention to Improve Symptoms of Atopic Dermatitis: a Feasibility Study

Br J Dermatol, 2022; 187: e80-e133. Revolutionizing Atopic Dermatitis, 9–11 April 2022.

Gudmundsdottir SL, Ballarini T, Ámundadóttir ML, Mészáros J, Eysteinsdottir JH, Thorleifsdottir RH, Ulfsdottir H, Hrafnkelsdottir SK, Bragadottir HB, Helgadottir H, Oddsson S, Silverberg J.

conference abstract

Oncology

App-Based Lifestyle Coaching (PINK!) Accompanying Breast Cancer Patients and Survivors to Reduce Psychological Distress and Fatigue and Improve Physical Activity: A Feasibility Pilot Study

Breast Care, 18(5), 354-365

Wolff J, Wuelfing P, Koenig A, Ehrl B, Damsch J, Smollich M, Baumann FT, Harbeck N, Wuerstlein R

Peer reviewed paper

App-based support for breast cancer patients to reduce psychological distress during therapy and survivorship – a multicentric randomized controlled trial

Frontiers in Oncology, 14, 1354377

Wolff J, Seidel S, Wuelfing P, Lux MP, zu Eulenburg C, Smollich M, Baumann F, Seitz S, Kuemmel S, Thill M, Tio J, Braun M, Hollaender H, Seitz A, Horn F, Harbeck N, Wuerstlein R

Peer reviewed paper

App-Based Lifestyle Intervention (PINK! Coach) in Breast Cancer Patients—A Real-World-Data Analysis

Cancers, 16(5), 1020

Wolff J, Smollich M, Wuelfing P, Mitchell J, Wuerstlein R, Harbeck N, Baumann F

Peer reviewed paper

Digitale Begleitung der Therapie und Nachsorge beim Mammakarzinom

Die Onkologie, 1-6

Würstlein R, Wolff J, Harbeck N, Wülfing P

Peer reviewed paper

Digital health program for patients with cancer to support self-management: A retrospective real-world analysis.

Presented at ASCO 2024

Bjarnadottir, O. K., Dobies, B., Isberg, A., White, A. J., Jónasdóttir, S., & Oddsson, S.

Conference abstract

Evaluating the Feasibility of a Digital Therapeutic Program for Patients With Cancer During Active Treatment: Pre-Post Interventional Study

JMIR Form Res 2022;6(10):e39764.

Gudmunsson GH, Mészáros J, Björnsdóttir, Ámundadóttir ML, Thorvardardottir GE, Magnusdottir E, Helgadottir H, Oddson S.

peer reviewed paper

A Digital Therapeutic Intervention for Breast Cancer Patients During Active Treatment: A Feasibility Study

Annals of Oncology, Volume 33, S230. Abstract Book of ESMO Breast Cancer 2022, Berlin, Germany, 03-05 May 2022

G. E. Thorvardardottir, H. Gudmundsson, J. Mészáros, A.E. Bjornsdottir, M.L. Amundadottir, O.K. Bjarnadottir, E. Magnusdottir, H. Helgadottir, S. Oddson

conference abstract

Cardiovascular

Empowering patients with heart failure: a digital health solution improved self-care and metabolic outcomes in a randomized controlled trial

European Heart Journal 45. Supplement_1 (2024): ehae666-1032

D O Arnar, E F Gudmundsson, B Dobies, S Sigurdardottir, T J Hrafnkelsdottir, H Broddadottir, G J Gudlaugsdottir, B Laxdal, L Asgeirsdottir, B Kaernested, H B Bragadottir, A Isberg, H Helgadottir, A F Sigurdsson, S J Oddsson

Conference abstracts

Remote patient monitoring with a digital health program: high compliance, retention, and engagement in a randomized study of patients with heart failure

Heart Failure 2024

DO Arnar, E Gudmundsson, A Isberg, S Sigurdardottir, TJ Hrafnkelsdottir, H Broddadottir, A Ketilsdottir, GJ Gudlaugsdottir, B Laxdal, L Asgeirsdottir, HB Bragadottir, B Dobies, H Helgadottir, AF Sigurdsson, SJ Oddsson, University of Iceland (Reykjavik Iceland), Sidekick Health (Kopavogur Iceland), Landspitali University Hospital (Reykjavik Iceland), Reykjavik Heart Center (Kopavogur Iceland)

Conference abstract

Improving outpatient care for heart failure through digital innovation: a feasibility study.

Pilot and Feasibility Studies. 2022;8:242

Arnar DO, Oddsson SJ, Gunnarsdottir T, Gudlaugsdottir GJ, Gudmundsson EF, Ketilsdóttir A, Halldorsdottir H, Hrafnkelsdottir TJ, Hallsson H, Amundadottir ML, Thorgeirsson T

peer reviewed paper

Improving outpatient care and symptoms for heart failure patients through digital innovation: a feasibility study.

European Journal of Heart Failure. 2021;23(Suppl S2):119. Abstracts of the Heart Failure 2021 and the World Congress on Acute Heart Failure, Online. 29 June - 1 July 2021

Arnar DO, Oddsson SJ, Gunnarsdottir T, Gudlaugsdottir GJ, Ketilsdottir A, Hrafnkelsdottir TJ, Halldorsdottir H, Amundadottir ML, Hallsson H, Thorgeirsson T.

conference abstract

A Novel Digital Therapeutic Program is Feasible for Patients with Peripheral Artery Disease.

Circulation, 2022;145(Suppl1):AP044. Abstracts of the American Heart Association Epidemiology and Prevention, Lifestyle and Cardiometabolic Health conference. Chicago IL. March 1-4, 2022

Oddsson SJ, Wahlgren CM, Nordanstig J, Gottsäter A, Gunnarsdottir T, Ulfsdottir H, Gudmundsson EF, Bjornsdottir AE, Thorgeirsson T.

conference abstract

A Digital Therapeutic Intervention is Feasible for Outpatient Care in Coronary Artery Disease.

Circulation, 2022;145(Suppl1):AP049. Abstracts of the American Heart Association Epidemiology and Prevention, Lifestyle and Cardiometabolic Health conference, Chicago IL. March 1-4, 2022

Arnar DO, Oddsson SJ, Gunnarsdottir T, Olafsdottir IV, Guömundsdottir MV, Loftsson KH, Gudmundsson EF, Kaernested B, Amundadottir ML, Sigurdardottir S, Mogensen B, Libungan B, Thorgeirsson T.

conference abstract

Metabolic

Apps auf Rezept für die Behandlung von Adipositas: die Wirksamkeit von zanadio im Versorgungsalltag

Adipositas - Ursachen, Folgeerkrankungen, Therapie 2024; 18(03): 160

K. Wiencke, A. Grannell

Conference abstract

Effects of Exercise and a Lifestyle App on Sleep-Disordered Breathing, Physical Health, and quality of Life

ERJ Open Research 2024 01134-2024; DOI: https://doi.org/10.1183/23120541.01134-2024

Katrin Y. Fridgeirsdottir, Conor J. Murphy, Anna Sigridur Islind, Birta S. Árnadóttir, Harald Hrubos-Strøm, Erna S. Arnardottir, Jose M. Saavedra

Original Research Article

Exercise therapy as a digital therapeutic for chronic disease management: consideration for clinical product development

Frontiers in Digital Health, 5, 1250979

Grannell A, Hallson H, Gunlaugsson B, Jonsson H

Peer reviewed paper

Neue Technologie - individuelle Möglichkeiten? Prädiktoren des Gewichtsverlustes mit der digitalen Gesundheitsanwendung zanadio

Diabetologie und Stoffwechsel 2023; 18(S 01): S26

Wiencke K, Roth L, Mehl N, Forkmann K

Conference abstract

The Effect of Multimodal App-based Interventions on Glycemic Control in Patients with Type 2 Diabetes: Systematic Review and Meta-Analysis

Conference abstract presented at DDG 2024

Bodner E, Roth L, Wiencke K, Bischoff C & Schwarz P

Peer reviewed paper

A randomized-controlled trial to evaluate the app-based multimodal weight loss program zanadio for patients with obesity

Obesity

Roth, L., Ordnung, M., Forkmann, K., Mehl, N., & Horstmann, A.

Peer-reviewed paper

Sustained Improvements in Liver Fat Reduction and Cardiometabolic Health at Nine Months After a 12 Week Digital Health Program in Individuals With Non-Alcoholic Fatty Liver Disease—A Feasibility Study.

Presented at EPI|Lifestyle 2024

jornsdottir, S., Ulfsdottir, H., Gudmundsson, E. F., Dobies, B., Sveinsdottir, K., Isberg, A. P., Bjornsdottir, G., Sigurdsson, S., Oddsson, S., & Gudnason, V.

Conference Poster

User Engagement, Acceptability and Clinical Markers in a Digital Health Program for Non-Alcoholic Fatty Liver Disease (NAFLD): A feasibility study

JMIR Cardio

Björnsdottir, S., Ulfsdottir, H., Gudmundsson, E. F., Sveinsdottir, K., Isberg, A., Dobies, B., Magnusdottir, G. E. A., Gunnarsdottir, T., Karlsdottir, T., Bjornsdottir, G., Sigurdsson, S., Oddsson, S., & Gudnason, V.

Peer-reviewed paper

Improved Metabolic Outcomes in Individuals with Type 2 Diabetes and Nonalcoholic Fatty Liver Disease after a Digital Intervention

Presented at ADA 2023

Bjornsdottir S, Ulfsdottir H, Gudmundsson E F, Sveinsdottir K, Isberg A P, Bjornsdottir G, Sigurdsson S, Oddsson S, & Gudnason V

Conference Abstract

Reduced Liver Fat and Improved Cardiometabolic Health in Individuals With Non Alcoholic Fatty Liver Disease After a 12 Week Digital Intervention - A Feasibility Study

Presented at EPI|Lifestyle 2023

Bjornsdottir S, Ulfsdottir H, Gudmundsson EF, Sveinsdottir K, Isberg AP, Bjornsdottir G, Sigurdsson S, Oddsson S, Gudnason V

Conference abstract

Effects of a Gamified Mobile Application to Support a Lifestyle-Change Program in Adults: A Controlled Pilot.

Diabetes, 2017;66(Supplement_1):A42. Abstract presented at the American Diabetes Association’s 77th Scientific Sessions, 9-13 June 2017, San Diego, CA.

Oddsson, S.

conference abstract

See also https://www.medscape.com/viewarticle/882130 for a brief coverage on study findings by Medscape.

A Digital Lifestyle Program in Outpatient Treatment of Type 2 Diabetes: A Randomized Controlled Study.

Journal of Diabetes Science and Technology. 2021;15(5):1134-1141. PMID: 32680441

Hilmarsdottir, E, Sigurdardottir, AK, Arnardottir, RH.

peer reviewed paper

Randomized Trial for Weight Loss Using a Digital Therapeutic Application.

Journal of Diabetes Science and Technology. March 2021. doi:10.1177/19322968211000815 Epub ahead of print. PMID: 33736484.

Thorgeirsson T, Torfadottir JE, Egilsson E, Oddsson SJ, Gunnarsdottir T, Aspelund T, Olafsdottir AS, Valdimarsdottir UA, Kawachi I, Adami H, Bjarnason RG.

peer reviewed paper